Formulary
Carmustine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Carmustine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Carmustine [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Carmustine [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Brain tumours,Multiple myeloma,Non-Hodgkin's lymphomas,Hodgkin's disease**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Contraindications
For carmustine [Specialist drug] Acute porphyrias
Side effects
For carmustine [Specialist drug] General side-effects: Common or very common Alopecia; anaemia; ataxia; constipation; diarrhoea; dizziness; headache; nausea; seizures; vomiting Specific side-effects: Common or very common When used by implant Abdominal pain; abscess; anxiety; asthenia; chest pain; coma; confusion; conjunctival oedema; depression; diabetes mellitus; drowsiness; dysphagia; electrolyte imbalance; embolism and thrombosis; eye pain; faecal incontinence; fever; gait abnormal; haemorrhage; hallucination; healing impaired; hydrocephalus; hyperglycaemia; hypersensitivity; hypertension; hypotension; increased risk of infection; injury; insomnia; intracranial pressure increased; leucocytosis; memory loss; meningitis; oedema; pain; paralysis; paranoia; peripheral neuropathy; personality disorder; rash; sensation abnormal; sepsis; speech impairment; stupor; thinking abnormal; thrombocytopenia; tremor; urinary incontinence; vision disorders With intravenous use Acute leukaemia; appetite decreased; bone marrow depression; encephalopathy (with high doses); hepatotoxicity; interstitial lung disease; myelodysplastic syndrome (following long term use); ocular toxicity; pulmonary fibrosis; respiratory disorders; retinal haemorrhage; stomatitis Uncommon When used by implant Cerebral infarction; intracranial haemorrhage Rare or very rare With intravenous use Gynaecomastia; nephrotoxicity (cumulative); peripheral vascular disease (with high doses) Frequency not known With intravenous use Infertility; myalgia Side-effects, further information Pulmonary toxicity Lung infiltration, pulmonary fibrosis, pneumonitis, and interstitial lung disease have been reported with intravenous use, some of which have been fatal. These appear to be dose-related, cumulative, and may be delayed. Hepatotoxicity Hepatotoxicity has been reported to occur with high intravenous doses, and may be delayed up to 60 days after administration; usually reversible.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Carmustine [Specialist drug] in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

