Formulary
Carboprost: Indications, Dosing, Side Effects and Interactions
Carboprost clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Carboprost: Indications, Dosing, Side Effects and Interactions
Carboprost clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Postpartum haemorrhage due to uterine atony in patients unresponsive to ergometrine and oxytocin**
- **Adult** (By Deep Intramuscular Injection): 250 micrograms, repeated if necessary, to be given at intervals of not less than 15 minutes. Total dose should not exceed 2 mg (8 doses).
Cautions
Excessive dosage may cause uterine rupture; history of anaemia; history of asthma; history of cardiovascular disease; history of diabetes; history of epilepsy; history of glaucoma; history of hypertension; history of hypotension; history of jaundice; history of pulmonary disease; history of raised intra-ocular pressure; uterine scars
Contraindications
Cardiac disease; pulmonary disease; untreated pelvic infection
Side effects
Common or very common Chills; cough; diarrhoea; headache; nausea; uterine disorders; vasodilation; vomiting Uncommon Abdominal pain upper; asthma; back pain; breast tenderness; chest discomfort; dizziness; drowsiness; dry mouth; dyspnoea; eye pain; haemorrhage; hiccups; hyperhidrosis; hypertension; increased risk of infection; movement disorders; muscle complaints; paraesthesia; pelvic pain; respiratory disorders; septic shock; sleep disorder; syncope; tachycardia; taste altered; tinnitus; uterine injuries; vertigo; vision blurred Frequency not known Anxiety; asthenia; blepharospasm; choking sensation; palpitations; rash; thirst; throat complaints; thyrotoxic crisis
Hepatic impairment
Manufacturer advises avoid in active hepatic disease.
Renal impairment
Manufacturer advises avoid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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