Formulary
Belumosudil: Indications, Dosing, Side Effects and Interactions
Belumosudil clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Belumosudil: Indications, Dosing, Side Effects and Interactions
Belumosudil clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Chronic graft-versus-host disease (under expert supervision)**
- **Adult** (By Mouth): 200 mg once daily.
**Chronic graft-versus-host disease (under expert supervision) for belumosudil**
- **Child 12-17 years** (By mouth): 200 mg once daily.
Side effects
Common or very common Anaemia; appetite decreased; arthralgia; asthenia; constipation; cough; diarrhoea; dizziness; dyspnoea; fever; gastrointestinal discomfort; headache; hyperglycaemia; hypertension; increased risk of infection; leucopenia; malaise; muscle spasms; nausea; neutropenia; oedema; pain; peripheral neuropathy; pruritus; swelling; vomiting; weight decreased Frequency not known Microangiopathic haemolytic anaemia; multi organ failure
Pregnancy
Avoid-toxicity in animal studies. M
Breast feeding
Avoid during treatment and for at least 1 week after the last treatment-no information available. M
Hepatic impairment
Caution in severe impairment (no information available); increased exposure in mild or moderate impairment-no dose adjustment required. M
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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