Formulary
Avelumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Avelumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Avelumab [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Avelumab [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Merkel cell carcinoma,Renal cell carcinoma,Urothelial carcinoma**
- **Adult** (By Intravenous Infusion): Specialist drug - access specialist resources for dosing information.
Side effects
For avelumab [Specialist drug] Common or very common Anaemia; appetite decreased; arthralgia; asthenia; back pain; chills; constipation; cough; diarrhoea; dizziness; dry mouth; dyspnoea; fever; gastrointestinal discomfort; headache; hypertension; hyperthyroidism; hyponatraemia; hypothyroidism; influenza like illness; infusion related reaction; interstitial lung disease; lymphopenia; myalgia; nausea; nerve disorders; peripheral oedema; skin reactions; thrombocytopenia; vomiting; weight decreased Uncommon Adrenal hypofunction; arthritis; eosinophilia; flushing; gastrointestinal disorders; hepatic disorders; hyperglycaemia; hypersensitivity; hypotension; myositis; nephritis; neuromuscular dysfunction; renal failure; thyroiditis Rare or very rare Cardiac inflammation; diabetes mellitus; hypopituitarism; pancreatitis; systemic inflammatory response syndrome; uveitis Frequency not known Endocrine disorders Side-effects, further information Infusion-related reactions Manufacturer advises permanently discontinue treatment in patients with grade 3 or 4 infusion-related reactions. Immune-related reactions Most immune-related adverse reactions are reversible and managed by temporarily stopping treatment and administration of a corticosteroid.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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