Formulary
Anidulafungin: Indications, Dosing, Side Effects and Interactions
Anidulafungin clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Anidulafungin: Indications, Dosing, Side Effects and Interactions
Anidulafungin clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Invasive candidiasis**
- **Adult** (By Intravenous Infusion): Initially 200 mg once daily for 1 day, then 100 mg once daily.
Side effects
Common or very common Bronchospasm; cholestasis; diarrhoea; dyspnoea; headache; hyperglycaemia; hypertension; hypokalaemia; hypotension; nausea; seizure; skin reactions; vomiting Uncommon Abdominal pain upper; coagulation disorder; vasodilation
Interactions
**Other interactions (3):**
- Anidulafungin is not a clinically relevant substrate, inducer, or inhibitor of cytochrome P450 isoenzymes (1A2, 2B6, 2C8, 2C9, 2C19, 2D6, 3A).
- Drug interaction studies were performed with anidulafungin and other medicinal products likely to be co-administered.
- No dosage adjustment of either medicinal product is recommended when anidulafungin is co-administered with ciclosporin, voriconazole or tacrolimus, and no dosage adjustment for anidulafungin is...
Pregnancy
Manufacturer advises avoid unless potential benefit outweighs risk-toxicity in animal studies.
Breast feeding
Manufacturer advises avoid unless potential benefit outweighs risk-present in milk in animal studies.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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