Formulary
Alpelisib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Alpelisib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Alpelisib [Specialist drug]: Indications, Dosing, Side Effects and Interactions
Alpelisib [Specialist drug] clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Breast cancer**
- **Adult** (By Mouth): Specialist drug - access specialist resources for dosing information.
Contraindications
For alpelisib [Specialist drug] History of severe cutaneous reactions; osteonecrosis of the jaw
Side effects
For alpelisib [Specialist drug] Common or very common Acute kidney injury; alopecia; anaemia; angioedema; appetite decreased; asthenia; dehydration; diarrhoea; dry eye; dry mouth; electrolyte imbalance; eyelid oedema; fever; gastrointestinal discomfort; headache; hypersensitivity; hypertension; increased risk of infection; insomnia; interstitial lung disease; lymphoedema; mucosal abnormalities; muscle complaints; nausea; oedema; oral disorders; osteonecrosis of jaw; skin reactions; taste altered; urosepsis; vision blurred; vomiting; vulvovaginal dryness; weight decreased Uncommon Diabetic ketoacidosis; ketoacidosis; pancreatitis; severe cutaneous adverse reactions (SCARs) Frequency not known Dyspnoea; gastrointestinal disorders; hyperglycaemia; hyperglycaemic hyperosmolar nonketotic syndrome; pleural effusion
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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