Formulary
Alcohol: Indications, Dosing, Side Effects and Interactions
Alcohol clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Alcohol: Indications, Dosing, Side Effects and Interactions
Alcohol clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Skin preparation before injection**
- **Child** (To The Skin): Apply as required.
- **Adult** (To The Skin): Apply as required.
**Skin preparation before injection for alcohol**
- **Child** (To the skin): Apply as required.
Cautions
Avoid broken skin; flammable; patients have suffered severe burns when diathermy has been preceded by application of alcoholic skin disinfectants
Contraindications
Neonates
Side effects
Features of acute alcohol intoxication include ataxia, dysarthria, nystagmus, and drowsiness, which may progress to coma, with hypotension and acidosis. For details on the management of poisoning, see Alcohol, under Emergency treatment of poisoning .
Interactions
**Severe interactions:**
- Data from a safety and tolerability study of co-administration of naltrexone with acamprosate in non-treatment seeking, alcohol dependent individuals showed that naltrexone administration...
- Inducers of CYP2E1 Medicinal products and compounds that increase the activity of cytochrome P450 isoenzyme CYP2E1, such as isoniazid and alcohol, may increase the metabolism of sevoflurane and lead...
- Alcohol should not be taken during pyrazinamide treatment, as this could increase the risk of damage to the liver and significantly impair reactivity.
- In a single-dose three-way crossover design study evaluating healthy subjects, the mean maximum reduction in diastolic blood pressure was significantly greater following avanafil administered in...
- Patients should therefore be advised to avoid alcoholic beverages while taking mirtazapine.
**Other interactions (234):**
- Dosulepin may alter the pharmacological effect of some concurrently administered drugs including CNS depressants such as alcohol and narcotic analgesics; the effect of these will be potentiated as...
- Macrogol raises the solubility of medicinal products that are soluble in alcohol and relatively insoluble in water.
- Sildenafil (50mg) did not potentiate the hypotensive effects of alcohol in healthy volunteers with mean maximum blood alcohol levels of 80 mg/dl.
- Concurrent intake of drugs with blood pressure lowering properties e.g.
- Centrally-acting medicinal products and alcohol OKEDI should be used with caution in combination with other centrally-acting substances, notably including alcohol, opiates, antihistamines and...
- The concomitant administration of this product with other medication such as central nervous system depressants (including alcohol and anaesthetics) or antihypertensives, opioids, anticholinergic or...
Medicinal forms
Medicinal forms No licensed medicines listed.
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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