Formulary
Albumin solution: Indications, Dosing, Side Effects and Interactions
Albumin solution clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Albumin solution: Indications, Dosing, Side Effects and Interactions
Albumin solution clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Acute or sub-acute loss of plasma volume e.g. in burns, pancreatitis, trauma, and complications of surgery (with isotonic solutions),Plasma exchange (with isotonic solutions),Severe hypoalbuminaemia associated with low plasma volume and generalised oedema where salt and water restriction with plasma volume expansion are required (with concentrated solutions 20%),Paracentesis of large volume ascites associated with portal hypertension (with concentrated solutions 20%)**
- **Adult** (By Intravenous Infusion): (consult product literature).
**Acute or sub-acute loss of plasma volume e.g. in burns, pancreatitis, trauma, and complications of surgery (with isotonic solutions), Plasma exchange (with isotonic solutions), Severe hypoalbuminaemia associated with low plasma volume and generalised oedema where salt and water restriction with plasma volume expansion are required (with concentrated solutions 20%), Paracentesis of large volume ascites associated with portal hypertension (with concentrated solutions 20%) for albumin solution**
- **Child** (By intravenous infusion): (consult product literature).
**Adjunct in the treatment of hyperbilirubinaemia by exchange transfusion in the newborn (with concentrated solutions 20%) for albumin solution**
- **Child** (By intravenous infusion): (consult product literature).
Cautions
Correct dehydration when administering concentrated solution; history of cardiovascular disease; increased capillary permeability; risk of haemodilution (e.g. severe anaemia or haemorrhagic disorders); risk of hypervolaemia (e.g. oesophageal varices or pulmonary oedema); vaccination against hepatitis A and hepatitis B may be required Cautions, further information Volume status Manufacturer advises adjust dose and rate of infusion to avoid fluid overload.
Side effects
Rare or very rare Fever; flushing; nausea; shock; urticaria
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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