Formulary
Agalsidase beta: Indications, Dosing, Side Effects and Interactions
Agalsidase beta is a form of recombinant human alpha-galactosidase A used for long-term enzyme replacement therapy in Fabry's disease.
MedNext Academy | 3 min read
Agalsidase beta: Indications, Dosing, Side Effects and Interactions
Agalsidase beta is a form of recombinant human alpha-galactosidase A used for long-term enzyme replacement therapy in Fabry's disease.
Drug action
Agalsidase beta is a form of recombinant human alpha-galactosidase A used for long-term enzyme replacement therapy in Fabry's disease.
Indications and dose
**Fabry's disease (under expert supervision)**
- **Adult** (By Intravenous Infusion): 1 mg/kg every 2 weeks.
**Fabry's disease (under expert supervision) for agalsidase beta**
- **Child 8-17 years** (By intravenous infusion): 1 mg/kg every 2 weeks.
Side effects
Common or very common Angioedema; arrhythmias; arthralgia; asthenia; chest discomfort; chills; cough; diarrhoea; dizziness; drowsiness; dyspnoea; eye disorders; fever; gastrointestinal discomfort; headache; hypertension; hyperthermia; hypotension; increased risk of infection; muscle complaints; musculoskeletal stiffness; nasal complaints; nausea; oedema; oral hypoaesthesia; pain; pallor; palpitations; respiratory disorders; sensation abnormal; skin reactions; syncope; temperature sensation altered; throat complaints; tinnitus; vasodilation; vertigo; vomiting Uncommon Dysphagia; ear discomfort; eye pruritus; influenza like illness; malaise; peripheral coldness; tremor Frequency not known Anaphylactoid reaction; hypersensitivity vasculitis; hypoxia Side-effects, further information Infusion-related reactions; manage by slowing the infusion rate, or minimise by pre-treatment with an antihistamine, antipyretic, or corticosteroid - consult product literature.
Pregnancy
Use with caution.
Breast feeding
Use with caution-no information available.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Agalsidase beta in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

