Formulary
Acrivastine: Indications, Dosing, Side Effects and Interactions
Acrivastine clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Acrivastine: Indications, Dosing, Side Effects and Interactions
Acrivastine clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Symptomatic relief of allergy such as hayfever, chronic idiopathic urticaria**
- **Child** (By Mouth): 12-17 years 8 mg 3 times a day.
- **Adult** (By Mouth): 8 mg 3 times a day.
**Symptomatic relief of allergy such as hayfever, chronic idiopathic urticaria for acrivastine**
- **Child 12-17 years** (By mouth): 8 mg 3 times a day.
Contraindications
Avoid in Acute porphyrias ; elderly (in adults)
Side effects
Common or very common Drowsiness; dry mouth Frequency not known Dizziness; rash Side-effects, further information Non-sedating antihistamines such as acrivastine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent.
Interactions
**Other interactions (4):**
- It is usual to advise patients not to undertake tasks requiring mental alertness whilst under the influence of alcohol and other CNS depressants.
- Concomitant administration of acrivastine may, in some individuals, produce additional impairment.
- There are no data to demonstrate an interaction between acrivastine and ketoconazole, erythromycin or grapefruit juice.
- However, due to known interactions between these compounds and other non-sedating antihistamines, caution is advised.
Pregnancy
Most manufacturers of antihistamines advise avoiding their use during pregnancy; however, there is no evidence of teratogenicity.
Breast feeding
Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.
Renal impairment
Avoid in severe impairment. M
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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