Formulary
Aclidinium bromide: Indications, Dosing, Side Effects and Interactions
Aclidinium bromide clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Aclidinium bromide: Indications, Dosing, Side Effects and Interactions
Aclidinium bromide clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Maintenance treatment of chronic obstructive pulmonary disease**
- **Adult** (By Inhalation Of Powder): 375 micrograms twice daily.
Cautions
For all antimuscarinics (inhaled) Bladder outflow obstruction; paradoxical bronchospasm; prostatic hyperplasia; susceptibility to angle-closure glaucoma Cautions, further information Elderly Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria to aid medication reviews (see Prescribing in the elderly for information): potentially inappropriate with a history of angle-closure glaucoma (may exacerbate glaucoma) or bladder outflow obstruction (may cause urinary retention). Cautions For aclidinium bromide Arrhythmia (when newly diagnosed within last 3 months); heart failure (hospitalisation with moderate or severe heart failure within last 12 months); myocardial infarction within last 6 months; unstable angina
Side effects
For all antimuscarinics (inhaled) Common or very common Arrhythmias; constipation; cough; dizziness; dry mouth; headache; nausea Uncommon Dysphonia; glaucoma; palpitations; skin reactions; stomatitis; urinary disorders; vision blurred Side-effects For aclidinium bromide Common or very common Diarrhoea; nasopharyngitis Uncommon Angioedema Rare or very rare Hypersensitivity
Interactions
**Other interactions (4):**
- Although no formal in vivo drug interaction studies have been performed with Duaklir Genuair, it has been used concomitantly with other COPD medicinal products including short-acting 2 -adrenergic...
- Hypokalaemic treatment Concomitant treatment with methylxanthine derivatives, steroids, or non-potassium-sparing diuretics may potentiate the possible hypokalaemic effect of 2 -adrenergic...
- Other pharmacodynamic interactions Duaklir Genuair should be administered with caution to patients being treated with medicinal products known to prolong the QTc interval such as monoamine oxidase...
- Formoterol does not inhibit the CYP450 enzymes at therapeutically relevant concentrations (see section 5.2).
Pregnancy
Manufacturer advises use only if potential benefit outweighs risk.
Breast feeding
Manufacturer advises only use if potential benefits outweigh risks.
Medicinal forms
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
Inside MedNext for this topic
- 411 MedNext-authored chapters
- 80,000+ MCQ bank
- 15 study modes
- Growing visual cheat sheets
Study modes
- Notes
- MCQ
- Audio
- Video
- Visual
- 3D Anatomy
- Trace
- Flashcards
- Mnemonics
- Image Bank
- Clinical
- Microscopy
- Audio QBank
- Cadaver
- Book Match
Continue reading
Subject HubPharmacology Hub
All pharmacology resources in one place.
Drug SchedulesIndian Drug Schedules
Schedule H, H1, X and G classifications.
FormularyBrowse all drugs
Search 1,850+ drug profiles.
Study Aclidinium bromide in the MedNext app
Challenge yourself with targeted pharmacology MCQs on this drug class. Every explanation links back to the chapter that teaches the concept.
Start drug challengeExplore the full formulary

