Formulary
Lanthanum: Indications, Dosing, Side Effects and Interactions
Lanthanum clinical drug profile including indications, dosing, side effects, cautions and interactions.
MedNext Academy | 3 min read
Lanthanum: Indications, Dosing, Side Effects and Interactions
Lanthanum clinical drug profile including indications, dosing, side effects, cautions and interactions.
Indications and dose
**Hyperphosphataemia in patients with chronic renal failure on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD),Hyperphosphataemia in patients with chronic kidney disease not on dialysis who have a serum-phosphate concentration of 1.78 mmol/litre or more that cannot be controlled by a low-phosphate diet**
- **Adult** (By Mouth): Hyperphosphataemia in patients with chronic renal failure on haemodialysis or continuous ambulatory peritoneal dialysis (CAPD), Hyperphosphataemia in patients with chronic kidney disease not on dialysis who have a serum-phosphate concentration of 1.78 mmol/litre or more that cannot be controlled by a low-phosphate diet 1.5-3 g daily in divided doses, dose to be adjusted according to serum-phosphate concentration every 2-3 weeks, to be taken with or immediately after meals.
Cautions
Gastro-intestinal disorders
Side effects
Common or very common Constipation; diarrhoea; electrolyte imbalance; gastrointestinal discomfort; gastrointestinal disorders; headache; nausea; vomiting Uncommon Alopecia; appetite abnormal; arthralgia; asthenia; burping; chest pain; dizziness; dry mouth; eosinophilia; hyperglycaemia; hyperhidrosis; hyperparathyroidism; increased risk of infection; irritable bowel syndrome; malaise; myalgia; oral disorders; osteoporosis; pain; peripheral oedema; taste altered; thirst; vertigo; weight decreased
Interactions
**Other interactions (2):**
- This restriction does not apply to lanthanum carbonate, as the co-administration of roxadustat with lanthanum carbonate did not result in a clinically meaningful change in the plasma exposure of...
- Chelation Complex Formation The simultaneous administration of ciprofloxacin (oral) and multivalent cation-containing drugs and mineral supplements (e.g.
Pregnancy
Manufacturer advises avoid-toxicity in animal studies.
Breast feeding
Manufacturer advises caution-no information available.
Hepatic impairment
Manufacturer advises caution (may be excreted in bile-possible risk of slower elimination and increased plasma concentrations in patients with reduced bile flow)-monitor liver function tests.
Medicinal forms
Tablet,Powder
Clinical governance
**Author:** MedNext Clinical Team. **Clinical reviewer:** Dr Shameer Deen, MBBS, MS, MRCS. **Sources:** BNF, Indian Pharmacopoeia, CIMS India. **Correction:** Report errors at support@mednext.academy.
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